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Last Update:
February, 28th 2007

DIESE SEITE AUF DEUTSCH
Papers

This is a collection of publications that emerged during or in context with the INTERGENOMICS project. They are sorted by year of publication and additionally alphabetically by first author's name.


2007


PathoPlant: a platform for microarray expression data to analyze co-regulated genes involved in plant defense responses.
Bülow L, Schindler M and Hehl R. (2007)
Nucleic Acids Res. 35 (Database issue), D841-D845.
Pubmed abstract here   ,   Pubmed Identifier: 17099232


SYSTOMONAS--an integrated database for systems biology analysis of Pseudomonas.
Choi C, Münch R, Leupold S, Klein J, Siegel I, Thielen B, Benkert B, Kucklick M, Schobert M, Barthelmes J, Ebeling C, Haddad I, Scheer M, Grote A, Hiller K, Bunk B, Schreiber K, Retter I, Schomburg D and Jahn D. (2007)
Nucleic Acids Res. 35 (Database issue), D553-D556
Pubmed abstract here   ,   Pubmed Identifier: 17202169


AthaMap web tools for the analysis and identification of co-regulated genes.
Galuschka C, Schindler M, Bülow L and Hehl R (2007)
Nucleic Acids Res. 35 (Database issue), D857-D862
Pubmed abstract here   ,   Pubmed Identifier: 17148485




2006


Beyond microarrays: Finding key transcription factors controlling signal transduction pathways.
Kel A, Voss N, Jauregui R, Kel-Margoulis O and Wingender E (2006)
BMC Bioinformatics 7 (Suppl 2), S13
Pubmed abstract here   ,   Pubmed Identifier: 17118134


AthaMap: from in silico data to real transcription factor binding sites.
Bülow L, Steffens NO, Galuschka C, Schindler M and Hehl R (2006)
In Silico Biology 6 , 0023
Pubmed abstract here   ,   Pubmed Identifier: 16922688


MetaQuant: a tool for the automatic quantification of GC/MS-based metabolome data.
Bunk B, Kucklick M, Jonas R, Münch R, Schobert M, Jahn D and Hiller K (2006)
Bioinformatics 22 (23), 2962-2965
Pubmed abstract here   ,   Pubmed Identifier: 17046977


TiProD: the Tissue-specific Promoter Database.
Chen X, Wu JM, Hornischer K, Kel A and Wingender E (2006)
Nucleic Acids Res. 34 (Database issue), D104-D107
Pubmed abstract here   ,   Pubmed Identifier: 16381824


LEGER: knowledge database and visualization tool for comparative genomics of pathogenic and non-pathogenic Listeria species.
Dieterich G, Kärst U, Fischer E, Wehland J and Jänsch L (2006)
Nucleic Acids Res. 34 (Database issue), D402-D406
Pubmed abstract here   ,   Pubmed Identifier: 16381897


TRANSPATH: an information resource for storing and visualizing signaling pathways and their pathological aberrations.
Krull M, Pistor S, Voss N, Kel A, Reuter I, Kronenberg D, Michael H, Schwarzer K, Potapov A, Choi C, Kel-Margoulis O and Wingender E (2006)
Nucleic Acids Res. 34 (Database issue), D546-D551
Pubmed abstract here   ,   Pubmed Identifier: 16381929


TRANSFAC and its module TRANSCompel: transcriptional gene regulation in eukaryotes.
Matys V, Kel-Margoulis OV, Fricke E, Liebich I, Land S, Barre-Dirrie A, Reuter I, Chekmenev D, Krull M, Hornischer K, Voss N, Stegmaier P, Lewicki-Potapov B, Saxel H, Kel AE and Wingender E (2006)
Nucleic Acids Res. 34 (Database issue), D108-110
Pubmed abstract here   ,   Pubmed Identifier: 16381825


EndoNet: an information resource about endocrine networks.
Potapov A, Liebich I, Dönitz J, Schwarzer K, Sasse N, Schöps T, Crass T and Wingender E (2006)
Nucleic Acids Res. 34 (Database issue), D540-D545
Pubmed abstract here   ,   Pubmed Identifier: 16381928


The Fnr regulon of Bacillus subtilis.
Reents H, Münch R, Dammeyer T, Jahn D and Härtig E (2006)
J. Bacteriol. 188 (3), 1103-1112
Pubmed abstract here   ,   Pubmed Identifier: 16428414


JProGO: a novel tool for the functional interpretation of prokaryotic microarray data using Gene Ontology information.
Scheer M, Klawonn F, Münch R, Grote A, Hiller K, Choi C, Koch I, Schobert M, Hätig E, Klages U and Jahn D (2006)
Nucleic Acids Res. 34 (Web Server issue), W510-W515
Pubmed abstract here   ,   Pubmed Identifier: 16845060


Composite Module Analyst: identification of transcription factor binding site combinations using genetic algorithm.
Waleev T, Shtokalo D, Konovalova T, Voss N, Cheremushkin E, Stegmaier P, Kel-Margoulis O, Wingender E and Kel A. (2006)
Nucleic Acids Res. 34 (Web Server issue), W541-W545
Pubmed abstract here   ,   Pubmed Identifier: 16845066




2005


VIS-O-BAC: exploratory visualization of functional genome studies from bacteria.
Dieterich G, Kärst U, Wehland J and Jänsch L (2005)
Bioinformatics 22 (5), 630-631
Pubmed abstract here   ,   Pubmed Identifier: 16339284


MineBlast: a literature presentation service supporting protein annotation by data mining of BLAST results.
Dieterich G, Kärst U, Wehland J and Jänsch L (2005)
Bioinformatics 21 (16), 3450-3451
Pubmed abstract here   ,   Pubmed Identifier: 15941742


JCat: a novel tool to adapt codon usage of a target gene to its potential expression host.
Grote A, Hiller K, Scheer M, Münch R, Nörtemann B, Hempel DC and Jahn D (2005)
Nucleic Acids Res. 33 (Web Server issue), W526-W531
Pubmed abstract here   ,   Pubmed Identifier: 15980527


Uracil content of 16S rRNA of thermophilic and psychrophilic prokaryotes correlates inversely with their optimal growth temperatures.
Khachane AN, Timmis KN and dos Santos VA (2005)
Nucleic Acids Res. 33 (13), 4016-4022
Pubmed abstract here   ,   Pubmed Identifier: 16030352


Virtual Footprint and PRODORIC: an integrative framework for regulon prediction in prokaryotes.
Münch R, Hiller K, Grote A, Scheer M, Klein J, Schobert M and Jahn D (2005)
Bioinformatics 21 (22), 4187-4189
Pubmed abstract here   ,   Pubmed Identifier: 16109747


Deriving an ontology for human gene expression sources from the CYTOMER database on human organs and cell types.
Michael H, Chen X, Fricke E, Haubrock M, Ricanek R and Wingender E (2005)
In Silico Biology 5 (1), 61-66
Pubmed abstract here   ,   Pubmed Identifier: 15972006


Topology of mammalian transcription networks..
Potapov AP, Voss N, Sasse N and Wingender E (2005)
Genome Inform. 16 (2), 270-278
Pubmed abstract here   ,   Pubmed Identifier: 16901109


Nanoarchaeum equitans creates functional tRNAs from separate genes for their 5'- and 3'-halves.
Randau L, Münch R, Hohn MJ, Jahn D and Söll D (2005)
Nature 433 (7025), 537-541
Pubmed abstract here   ,   Pubmed Identifier: 15690044


BRAGI: linking and visualization of database information in a 3D viewer and modeling tool.
Reichelt J, Dieterich G, Kvesic M, Schomburg D and Heinz DW (2005)
Bioinformatics 21 (7), 1291-1293
Pubmed abstract here   ,   Pubmed Identifier: 15546941


VBASE2, an integrative V gene database.
Retter I, Althaus HH, Münch R and Müller W (2005)
Nucleic Acids Res. 33 (Database issue), D671-D674
Pubmed abstract here   ,   Pubmed Identifier: 15608286


Evaluating phylogenetic footprinting for human-rodent comparisons.
Sauer T, Shelest E and Wingender E (2005)
Bioinformatics 22 (4), 430-437
Pubmed abstract here   ,   Pubmed Identifier: 16332706


Construction of predictive promoter models on the example of antibacterial response of human epithelial cells.
Shelest E and Wingender E (2005)
Theor. Biol. Med. Model. 2 (1), 2
Pubmed abstract here   ,   Pubmed Identifier: 15647113


AthaMap web tools for database-assisted identification of combinatorial cis-regulatory elements and the display of highly conserved transcription factor binding sites in Arabidopsis thaliana.
Steffens NO, Galuschka C, Schindler M, Bülow L and Hehl R (2005)
Nucleic Acids Res. 33 (Web Server issue), W397-W402
Pubmed abstract here   ,   Pubmed Identifier: 15980498


Genomic peculiarity of coding sequences and metabolic potential of probiotic Escherichia coli strain Nissle 1917 inferred from raw genome data.
Sun J, Gunzer F, Westendorf AM, Buer J, Scharfe M, Jarek M, Gössling F, Blöcker H and Zeng AP. (2005)
J Biotechnol. 117 (2), 47-61
Pubmed abstract here   ,   Pubmed Identifier: 15823404


Comparative proteome analysis of secretory proteins from pathogenic and nonpathogenic Listeria species.
Trost M, Wehmhöner D, Karst U, Dieterich G, Wehland J and Jänsch L (2005)
Proteomics 5 (6), 1544-1557
Pubmed abstract here   ,   Pubmed Identifier: 15838904


"LaneSpector", a tool for membrane proteome profiling based on sodium dodecyl sulfate-polyacrylamide gel electrophoresis/liquid chromatography-tandem mass spectrometry analysis: application to Listeria monocytogenes membrane proteins.
Wehmhöner D, Dieterich G, Fischer E, Baumgärtner M, Wehland J and Jänsch L (2005)
Electrophoresis 26 (12), 2450-2460
Pubmed abstract here   ,   Pubmed Identifier: 15966022




2004


PathoPlant®: A Database on Plant-Pathogen Interactions.
Bülow L, Schindler M, Choi C, and Hehl R (2004)
In Silico Biology 4 , 529-536
Pubmed abstract here   ,   Pubmed Identifier: 15752070


Consistent re-modeling of signaling pathways and its implementation in the TRANSPATH database.
Choi C, Crass T, Kel A, Kel-Margoulis O, Krull M, Pistor S, Potapov A, Voss N and Wingender E (2004)
Genome Inform. Ser. Workshop Genome Inform. 15 (2), 244-254
Pubmed abstract here   ,   Pubmed Identifier: 15706510


A method to determine the elementary flux modes in genome-based large scale metabolic network.
He F, Ma H, Yuan YJ, Deckwer WD and Zeng AP (2004)
Bioinformatics
submitted


Isolation and analysis of gene regulatory sequences.
Hehl R, Steffens NO and Wingender E (2004)
In: Handbook of Plant Biotechnology, Klee H, and Christou P, eds., (Wiley and Sons Ltd.) , 81-102



PrediSi: prediction of signal peptides and their cleavage positions.
Hiller K, Grote G, Scheer M, Münch R and Jahn D (2004)
Nucleic Acids Res. 32 (Web Server issue), W375-W379
Pubmed abstract here   ,   Pubmed Identifier: 15215414


Analysis of disturbed images.
Kauer G and Blöcker H (2004)
Bioinformatics 20 , 1381-1387
Pubmed abstract here   ,   Pubmed Identifier: 14962927


Phylogenetic comparison of metabolic capacities of organisms at genome level.
Ma H and Zeng AP (2004)
Molecular Phylogenetics and Evolution 31 (1), 204-213
Pubmed abstract here   ,   Pubmed Identifier: 15019620


Hierarchical structure and modules in the Escherichia coli transcriptional regulatory network revealed by a new top-down approach.
Ma HW, Buer J and Zeng AP (2004)
BMC Bioinformatics 5 , 199
Pubmed abstract here   ,   Pubmed Identifier: 15603590


Decomposition of metabolic network into functional modules based on the global connectivity structure of reaction graph.
Ma HW, Zhao XM, Yuan YJ and Zeng AP (2004)
Bioinformatics 20 (12), 1870-1876
Pubmed abstract here   ,   Pubmed Identifier: 15037506


Insights into the genomic basis of niche specificity of Pseudomonas putida strain KT2440.
Martins dos Santos VAP, Heim S, Nelson KE and Timmis KN (2004)
Environm. Microbiol. 6 (12), 1264-1286
Pubmed abstract here   ,   Pubmed Identifier: 15560824


AthaMap, an online resource for in silico transcription factor binding sites in the Arabidopsis thaliana genome.
Steffens NO, Galuschka C, Schindler M, Bülow L and Hehl R (2004)
Nucleic Acids Res. 32 (Database issue), D368-D372
Pubmed abstract here   ,   Pubmed Identifier: 14681436


Systematic DNA-binding domain classification of transcription factors.
Stegmaier P, Kel AE and Wingender E (2004)
Genome Inform. Ser. Workshop Genome Inform. 15 (2), 276-286
Pubmed abstract here   ,   Pubmed Identifier: 15706513


IdentiCS - Identification of coding sequence and in silico reconstruction of the metabolic network directly from unannotated low-coverage bacterial genome sequence.
Sun J and Zeng AP (2004)
BMC Bioinformatics 5 , 112
Pubmed abstract here   ,   Pubmed Identifier: 15312235


Iron availability, oxygen limitation, Pseudomonas aeruginosa and cystic fibrosis.
Zeng AP and Kim EJ (2004)
Microbiology 150 (3), 516-518
Pubmed abstract here   ,   Pubmed Identifier: 14993296




2003


Genome sequence completed of Alcanivorax borkumensis, a hydrocarbon-degrading bacterium that plays a global role in oil removal from marine systems.
Golyshin PN, Martins Dos Santos VA, Kaiser O, Ferrer M, Sabirova YS, Lunsdorf H, Chernikova TN, Golyshina OV, Yakimov MM, Pühler A and Timmis KN (2003)
J. Biotechnol. 106 , 215-220
Pubmed abstract here   ,   Pubmed Identifier: 14651863


JVirGel: calculation of virtual two-dimensional protein gels.
Hiller K, Schobert M, Hundertmark C, Jahn D and Münch R (2003)
Nucleic Acids Res. 31 (13), 3862-3865
Pubmed abstract here   ,   Pubmed Identifier: 12824438


Applying signal theory to the analysis of biomolecules.
Kauer G and Blöcker H (2003)
Bioinformatics 19 (16), 2016-2021
Pubmed abstract here   ,   Pubmed Identifier: 14594705


Iron deficiency leads to inhibition of oxygen transfer and enhanced formation of virulence factors in cultures of Pseudomonas aeruginosa PAO1.
Kim EJ, Sabra W and Zeng AP (2003)
Microbiology 149 , 2627-2634
Pubmed abstract here   ,   Pubmed Identifier: 12949186


TRANSPATH®: an integrated database on signal transduction and a tool for array analysis.
Krull M, Voss N, Choi C, Pistor S, Potapov A and Wingender E (2003)
Nucleic Acids Res. 31 (1), 97-100
Pubmed abstract here   ,   Pubmed Identifier: 12519957


PRODORIC: prokaryotic database of gene regulation.
Münch R, Hiller K, Barg H, Heldt D, Linz S, Wingender E and Jahn D (2003)
Nucleic Acids Res. 31 (1), 266-269
Pubmed abstract here   ,   Pubmed Identifier: 12519998


Reconstruction of metabolic networks from genome data and analysis of their global structure for various organisms.
Ma H and Zeng AP (2003)
Bioinformatics 19 , 270-277
Pubmed abstract here   ,   Pubmed Identifier: 12538249


The connectivity structure, giant strong component and centrality of metabolic networks.
Ma H and Zeng AP (2003)
Bioinformatics 19 (11), 1423-1430
Pubmed abstract here   ,   Pubmed Identifier: 12874056


Genomic features of Pseudomonas putida strain KT2440.
Martins dos Santos VAP, Timmis KN, Tümmler B and Weinel C (2003)
In: The Pseudomonads Vol I. Genomics, life style and molecular architecture, Chapter 3, Ramos J. (Ed.), 2003, Kluyver Academic Publishers, The Hague, The Netherlands 6 (12), 1264-1286
Pubmed abstract here   ,   Pubmed Identifier: 15560824


TRANSFAC: transcriptional regulation, from patterns to profiles.
Matys V, Fricke E, Geffers R, Gössling E, Haubrock M, Hehl R, Hornischer K, Karas D, Kel AE, Kel-Margoulis OV, Kloos DU, Land S, Lewicki-Potapov B, Michael H, Münch R, Reuter I, Rotert S, Saxel H, Scheer M, Thiele S and Wingender E (2003)
Nucleic Acids Res. 31 (1), 374-378
Pubmed abstract here   ,   Pubmed Identifier: 12520026


Alterations in the formation of lipopolysaccharide and membrane vesicles on the surface of Pseudomonas aeruginosa PAO1 under oxygen stress conditions.
Sabra W, Lunsdorf H and Zeng AP (2003)
Microbiology 149 , 2789-2795
Pubmed abstract here   ,   Pubmed Identifier: 14523112


Prediction of potential C/EBP/NF-kappaB composite elements using matrix-based search methods.
Shelest E, Kel AE, Gössling E and Wingender E (2003)
In Silico Biol. 3 (1), 71-79
Pubmed abstract here   ,   Pubmed Identifier: 12762847


Identification of ORF similar regions encoding metabolic enzymes for in silico reconstruction of metabolic networks from unannotated raw genome sequences.
Sun J and Zeng AP (2003)

submitted


A comparative genomic analysis of dha regulon and related genes for anaerobic glycerol metabolism in bacteria.
Sun J, van den Heuvel J, Soucaille P, Qu Y and Zeng AP (2003)
Biotechnol. Prog. 19 (2), 263-272
Pubmed abstract here   ,   Pubmed Identifier: 12675558


Combined use of proteomic analysis and enzyme activity assays for metabolic pathway analysis of glycerol fermentation by Klebsiella pneumoniae.
Wang W, Sun J, Hartlep M, Deckwer WD and Zeng AP (2003)
Biotechnol. Bioeng. 83 (5), 525-536
Pubmed abstract here   ,   Pubmed Identifier: 12827694


Protein identification from two-dimensional gel electrophoresis analysis of Klebsiella pneumoniae by combined use of mass spectrometry data and raw genome sequences.
Wang W, Sun J, Nimtz M, Deckwer WD and Zeng AP (2003)
Proteome Sci. 1 (1), 6
Pubmed abstract here   ,   Pubmed Identifier: 14653859




2002


TRANSCompel: a database on composite regulatory elements in eukaryotic genes.
Kel-Margoulis OV, Kel AE, Reuter I, Deineko IV and Wingender E (2002)
Nucleic Acids Res. 30 (1), 332-334
Pubmed abstract here   ,   Pubmed Identifier: 11752329


S/MARt DB: a database on scaffold/matrix attached regions.
Liebich I, Bode J, Frisch M and Wingender E (2002)
Nucleic Acids Res. 30 (1), 372-374
Pubmed abstract here   ,   Pubmed Identifier: 11752340


Mathematical models to characterise the physiological behaviour of immobilised cells.
Martins dos Santos VAP, Tramper J and Wijffels RH . In: Cell Immobilisation Biotechnology. Nedovic V. , Willaert R. (Eds). Focus on Biotechnology Series, 2002, Elsevier Publishers, The Hague, The Netherlands (2002)
In: Cell Immobilisation Biotechnology. Nedovic V. , Willaert R. (Eds). Focus on Biotechnology Series



Metabolic control analysis of eucaryotic pyruvate dehydrogenase multienzyme complex.
Modak J, Deckwer WD and Zeng AP (2002)
Biotechnol. Prog. 18 (6), 1157-1169
Pubmed abstract here   ,   Pubmed Identifier: 12467446


Complete genome sequence and comparative analysis of the metabolically versatile Pseudomonas putida KT2440.
Nelson KE, Weinel C, Paulsen IT, Dodson RJ, Hilbert H, Martins dos Santos VA, Fouts DE, Gill SR, Pop M, Holmes M, Brinkac L, Beanan M, DeBoy RT, Daugherty S, Kolonay J, Madupu R, Nelson W, White O, Peterson J, Khouri H, Hance I, Chris Lee P, Holtzapple E, Scanlan D, Tran K, Moazzez A, Utterback T, Rizzo M, Lee K, Kosack D, Moestl D, Wedler H, Lauber J, Stjepandic D, Hoheisel J, Straetz M, Heim S, Kiewitz C, Eisen J, Timmis KN, Dusterhoft A, Tummler B and Fraser CM (2002)
Environ Microbiol. 4 , 799-808
Pubmed abstract here   ,   Pubmed Identifier: 12534463


Physiological responses of Pseudomonas aeruginosa PAO1 to oxidative stress in controlled microaerobic and aerobic culture.
Sabra W, Kim EJ and Zeng AP (2002)
Microbiology 148 (148), 3195-3202
Pubmed abstract here   ,   Pubmed Identifier: 12368453


Rekonstruktion und Simulation des metabolischen Netzwerks von Pseudomonas aeruginosa für die Bildung von Virulenzfaktoren.
Sabra W, Ma H, Wang W, Kim EJ and Zeng AP (2002)
Chem.-Ing. Tech. 74 , 688



Nonlinear dynamics of eucaryotic pyruvate dehydrogenase multienzyme complex: decarboxylation rate, oscillations, and multiplicity.
Zeng AP, Modak J and Deckwer WD (2002)
Biotechnol. Prog. 18 (6), 1265-1276
Pubmed abstract here   ,   Pubmed Identifier: 12467461




2001


Database-assisted promoter analysis.
Hehl R and Wingender E (2001)
Trends Plant Sci. 6 , 251-255
Pubmed abstract here   ,   Pubmed Identifier: 11378466


The TRANSPATH signal transduction database: a knowledge base on signal transduction networks.
Schacherer F, Choi C, Götze U, Krull M, Pistor S and Wingender E (2001)
Bioinformatics 17 (11), 1053-1057
Pubmed abstract here   ,   Pubmed Identifier: 11724734


The TRANSFAC system on gene expression regulation.
Wingender E, Chen X, Fricke E, Geffers R, Hehl R, Liebich I, Krull M, Matys V, Michael H, Ohnhäuser R, Pr¨ss M, Schacherer F, Thiele S and Urbach S (2001)
Nucleic Acids Res. 29 (1), 281-283
Pubmed abstract here   ,   Pubmed Identifier: 11125113


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