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Goals The goal of the research and development of this competence center is to provide a range of bioinformatics tools that are suitable to model the interaction of genome-driven processes during the infection of mammalian and plant organisms. For that purpose, an integrated infrastructure shall be generated which comprises the knowledge bases, tools and services that already exist in this region as well as those which will be specifically developed in the course of this project. It is designed as a sustained and long-term concept with promising exploitation perspectives for the tools to be developed. Therefore, its consortium also comprises a commercial partner who could act as exploitation partner, but also will articulate the professional needs for bioinformatic achievements. Finally, the project also has a strong educational component which accomodates the interdisciplinary requirements of bioinformatics and which is supported by all partners of the competence center.